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Index > Protein center > SH3RF1(Gene name) > Bovine
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  • SH3RF1 (Gene name),
  • E3 ubiquitin-protein ligase SH3RF1 (Protein name ),  SH3R1_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    SH3RF1(POSH);
    Protein name:
    E3 ubiquitin-protein ligase SH3RF1;
    Alternative:
    SH3 domain-containing RING finger protein 1;Plenty of SH3s(Protein POSH);
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Interacts with Rac; in a GTP-dependent manner. Interacts with MAP3K10 and MAP3K11. Interacts with MAPK8IP; this interaction leads to the PJAC complex (POSH-JIP or SH3RF1/MAPK8IP apoptotic complex) with a 1:1 ratio. Interacts with SIAH1. Interacts with HERP1. Probably part of a signaling complex that may contain SH3RF1, MAPK8IP, DLK1, MAP2K4, MAP2K7, MAPK8, MAPK9, AKT1 and AKT2.
    Function:
    Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes such as UBE2D1 or UBE2N and then transfers it to substrates. In the absence of an external substrate, it can catalyze self-ubiquitination. Stimulates ubiquitination of potassium channel KCNJ1, enhancing it's dynamin-dependent and clathrin-independent endocytosis.
    Subcellular Location:
    Cytoplasm perinuclear region Cell projection lamellipodium Golgi apparatus trans-Golgi network Colocalizes, with AKT2, in lamellipodia (By similarity). Colocalizes, with HERP1, in trans-Golgi network.
    Protein Attributes:
    Sequence length:
    840
    Sequence:
    50:
    MDESALLDLL | ECPVCLERLD | ASAKVLPCQH | TFCKRCLLGI | VGSRNELRCP | 
    100:
    ECRTLVGSGV | EQLPSNILLV | RLLDGIKQRP | WKPGPVGGSG | TNGTSALRAQ | 
    150:
    SSAVVTCSPK | DGPSSQGGPQ | PRAQAWSPPV | RGIPQLPCAK | ALYNYEGKEP | 
    200:
    GDLKFSKGDI | IVLRRQVDEN | WYHGEVGGVH | GFFPTNFVQI | IKPLPQPPPQ | 
    250:
    CKALYDFEVK | DKEADKDCLP | FAKDDVLTVI | RRVDENWAEG | MLADKIGIFP | 
    300:
    ISYVEFNSAA | KQLIEWDQPP | GPGVAAGEGA | LATTPSSTTT | KQPDGKKNTK | 
    350:
    KRHSFTSLSM | ASKASQAAQQ | RHSMEISPPV | LISSSNPAAA | ARIGELAGLS | 
    400:
    CSAPSQVHIS | TTGLIVTPPP | SSPVTTGPSF | TFPAEAPYPA | ALATLNPPLP | 
    450:
    PPPLQAATPT | GTAVAAAAGM | GPRPTAGPTD | QTTHPRPQPR | PSVYVAIYPY | 
    500:
    TPRKEDELEL | RKGEMFLVFE | RCQDGWFKGT | SMHTSKIGVF | PGNYVAPVTR | 
    550:
    AVTSASQGKV | PMLTTGPASR | GGVLANPPST | GGPAQKPPGN | GVAGGPGVPT | 
    600:
    AVVSAAHVQT | SPQAKVLLHA | SGQMTVNQAR | SAARTVSAHS | QERPTAAVTP | 
    650:
    IQVQSTPGQS | HHPLVSPQPP | APLGPPAHAA | ASGLGRVGGP | LACATAPASI | 
    700:
    PAASLEPEPS | SRPATLLPGT | PTSPDSGSAA | RPDKDGKKEK | KGLLKLLSGA | 
    750:
    STKRKPRGSP | PASPTLDAEL | GAELSCGPPG | PPCACPGPCD | GDTMAPGPQR | 
    800:
    RASSLDSAPV | APPPRQPCSS | LGPAASEVRP | AVCERHRVVV | SYPPQSEAEL | 
    840:
    ELKEGDIVFV | HKKREDGWFK | GTLQRNGKTG | LFPGSFVENI | 
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    SMR:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine E3 ubiquitin-protein ligase SH3RF1
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    E15485h
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    MSDS:
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    96T
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    ELISA Kit for Bovine E3 ubiquitin-protein ligase SH3RF1
    Cat.:
    E15485m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Bovine E3 ubiquitin-protein ligase SH3RF1
    Cat.:
    E15485b
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Bovine E3 ubiquitin-protein ligase SH3RF1
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    E15485r
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    Packing:
    96T
    CLIA Kit for Bovine E3 ubiquitin-protein ligase SH3RF1
    Cat.:
    U15485m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Bovine E3 ubiquitin-protein ligase SH3RF1
    Cat.:
    U15485b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine E3 ubiquitin-protein ligase SH3RF1
    Cat.:
    U15485r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine E3 ubiquitin-protein ligase SH3RF1
    Cat.:
    U15485h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Bovine E3 ubiquitin-protein ligase SH3RF1
    Cat.:
    P15485Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine E3 ubiquitin-protein ligase SH3RF1
    Cat.:
    P15485Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine E3 ubiquitin-protein ligase SH3RF1
    Polyclonal Antibody for Bovine E3 ubiquitin-protein ligase SH3RF1
    Cat.:
    P15485Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Bovine E3 ubiquitin-protein ligase SH3RF1
    Monoclonal Antibody for Bovine E3 ubiquitin-protein ligase SH3RF1
    Monoclonal Antibody for Bovine E3 ubiquitin-protein ligase SH3RF1
    Monoclonal Antibody for Bovine E3 ubiquitin-protein ligase SH3RF1
    Protein for Bovine E3 ubiquitin-protein ligase SH3RF1
    Protein for Bovine E3 ubiquitin-protein ligase SH3RF1
    Protein for Bovine E3 ubiquitin-protein ligase SH3RF1
    Protein for Bovine E3 ubiquitin-protein ligase SH3RF1

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    References
    1. 1.
      NIH - Mammalian Gene Collection (MGC) project
      Submitted (2007-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Hereford.
      tissue: Hypothalamus.
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